Question of the Week AdARRC™ September 1, 2025 Question of the Week Question of the Week What is the first line of treatment for this condition?A 23-year-old woman with a history of systemic lupus erythematosus (SLE) develops a diffuse tense bullous eruption. A biopsy of the lesion shows subepidermal blistering with a dense neutrophilic infiltration in the upper dermis. Direct immunofluorescence shows significant granular immunoglobulin G (IgG) deposition at the dermoepidermal junction. Antibodies to type VII collagen are seen. A diagnosis of bullous lupus erythematosus (BLE) is made. A. Methylprednisolone B. Hydroxychloroquine C. Antibiotics D. Dapsone Share This Post!