More unfavorable outcomes with 6 weeks versus 12 weeks of oral antibiotic therapy for prosthetic joint infections
Question
What is the optimal duration of oral antibiotic therapy after surgical treatment for prosthetic hip or knee joint infections?
Conclusion
Following surgical treatment for prosthetic joint infections, a 6-week course of oral antibiotic therapy is not as effective as a 12-week course and leads to a higher number of persistent or recurrent infections at 2 years.