High-frequency spinal cord stimulation improves pain in patients with refractory painful diabetic neuropathy

Is high-frequency spinal cord stimulation added to conventional medical management effective in alleviating pain in persons with painful diabetic neuropathy refractory to medical therapy?

In this study with multiple biases in favor of intervention, patients with painful diabetic neuropathy treated with conventional medical management plus high-frequency spinal cord stimulation (CMM+SCS) experienced dramatic improvement compared with those who continued to use their previous ineffective therapy. Given the methodologic issues with this study, more rigorous trials are needed.