Tofacitinib Does Not Increase Risk of Venous Thromboembolism in Patients With RA

 Tofacitinib Does Not Increase Risk of Venous Thromboembolism in Patients With RA

Question

Does Tofacitinib Increase the Risk of Venous Thromboembolism in Patients with RA?

Conclusion

Recently, a link between venous thromboembolism (VTE) and Janus Kinase (JAK) inhibitors has emerged, causing the FDA to recommend a black box label for tofacitinib in 2019. New research, however, suggests that tofacitinib had similarly infrequent cases of VTE (<1 per 100) when compared with tumor necrosis factor inhibitors (TNFIs).

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