Question of the Week AdARRC™ May 26, 2025 Question of the Week Question of the Week A 68-year-old woman presents for a follow-up visit. Her medical history includes hypertension, osteoporosis, primary hyperparathyroidism, chronic kidney disease, and a history of venous thromboembolism (VTE). Her medications include lisinopril, a bisphosphonate, and long-term anticoagulation therapy. A recent dual-energy x-ray absorptiometry (DEXA) scan shows a T-score of -3.2, indicating severe osteoporosis and a high risk for fracture. Given her high fracture risk, the clinician is considering transitioning her to an anabolic agent, such as a parathyroid hormone-related protein (PTHrP) analog.Which of the following conditions is a contraindication to initiating this therapy? A. Primary hyperparathyroidism B. Chronic kidney disease C. Osteoarthritis D. History of venous thromboembolism Share This Post!
