Question
Are platelet-rich plasma injections effective for alleviating pain and improving function in adults with symptomatic ankle osteoarthritis?
Conclusion
This study found no evidence that supports a benefit of PRP injections compared with saline placebo injections for improving function or reducing pain in adults with symptomatic ankle osteoarthritis.
Reference
Paget LDA, Reurink G, de Vos RJ, et al, for the PRIMA Study Group. Effect of platelet-rich plasma injections vs placebo on ankle symptoms and function in patients with ankle osteoarthritis. A randomized clinical trial. JAMA 2021;326(16):1595-1605.
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