Question
What interventions are effective in managing patients with chronic low back pain?
Conclusion
The interventions that are better than control in achieving at least a 30% reduction in pain are exercise, oral nonsteroidal anti-inflammatory drugs (NSAIDs), duloxetine, and opioids, but discontinuations of the latter 2 treatments were common. Lower-quality data suggest that manipulation and topical capsaicin are also effective. Finally, it is possible the authors’ inclusion criteria missed important studies.
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